Diagnostic Criteria for Primary Aldosteronism

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Evolution of diagnostic criteria for primary aldosteronism: why is it more common in "drug-resistant" hypertension today?

The recent "epidemic" of primary aldosteronism reported in the literature is most likely related to the widespread acceptance that with easy access to accurate measurements of renin and aldosterone, it is no longer necessary to wait until hypokalemia has become profound before embarking on diagnostic testing to attempt to ferret out this most common cause of "essential" hypertension. This is es...

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New Advances in the Diagnostic Workup of Primary Aldosteronism

Primary aldosteronism is an important and common cause of hypertension that carries a high burden of morbidity. Outcomes, however, are excellent if diagnosed and treated appropriately. The diagnostic workup for primary aldosteronism is complex and comprises three steps: (1) screening, (2) confirmatory testing, and (3) subtype differentiation. In this review, we discuss recent advances in the di...

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Primary aldosteronism during long-term ulcerative colitis: a diagnostic challenge

Primary aldosteronism (PA) represents an important cause of secondary hypertension. Th is situation is currently increasingly being diagnosed accounting for more than 10% of patients with secondary hypertension [1]. It is characterized by a variety of clinical features including cardiovascular, renal, and metabolic consequences, especially hypokalemia [2]. Ulcerative colitis (UC) oft en require...

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Primary aldosteronism: diagnostic accuracy of the losartan and captopril tests.

BACKGROUND To assess whether angiotensin-II receptor blockers (ARBs) offer any additional advantage in confirming the diagnosis of primary aldosteronism (PA) and their use in the differentiation of PA subtypes. METHODS A prospective, cohort, head-to-head study was conducted between July 2003 and July 2006. A total of 135 patients received captopril and losartan tests to confirm the diagnosis ...

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Diagnostic value of the post-captopril test in primary aldosteronism.

Primary aldosteronism is a disorder with hypertension, hypokalemia, increased plasma aldosterone, and suppressed renin activity. A random plasma aldosterone/renin activity (PA/PRA) >65 (conventional units ratio [CUR] >30) has been proposed as a screening test. We have retrospectively determined the value of the post-captopril plasma aldosterone/renin activity (CAPT PA/PRA) test for the diagnosi...

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ژورنال

عنوان ژورنال: Nihon Naika Gakkai Zasshi

سال: 2007

ISSN: 0021-5384,1883-2083

DOI: 10.2169/naika.96.2539